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A GFR less than 60 mL per minute per 1. 73 m 2 represents loss of 50 of the adult level of normal renal function. Below this level, the prevalence of complications of chronic kidney disease increases. Ninety-eight percent of patients with chronic renal failure (CRF) in the United States begin dialysis when their GFR is less than 15 citness per minute per 1. 73 m 2. Preparations for renal transplantation and dialysis should begin when the GFR approaches 30 mL per minute per 1. 73 m 2.

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Diabetes Care. 1998;21:1122 1128, with permission. Figure 11-1 Estimated Cumulative Cost (Average per Patient) of Managing Complications of Type 2 Diabetes According to Type of Complication.

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